CRL-40,940(Fladrafinil) powder
CRL-40,940(Fladrafinil) powder

CRL-40,940(Fladrafinil) powder

Product Code: CAS:90280-13-0
Availability: 72
Price: $120.98
Ex Tax: $120.98

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Product Summary:

Chemical Name: 2-[bis(4-fluorophenyl)methylsulfinyl]acetamide
Synonyms: Lauflumide, Fluoromodafinil, Flmodafinil, Bisfluoromodafinil, N-deshydroxyl Fladrafinil, bis-(p)-fluoromodafinil, (2-Amino-2-oxoethyl)[bis(4-fluorophenyl)methyl]sulfoniumolate
CAS #: 90280-13-0 

Eugeroic related to Modafinil. Weak Dopamine Reuptake Inhibitor (DRI). Psychotonic.

Form: White to pale cream powder.
Molecular Formula:  C15H13F2NO3S

Molecular Weight:    309.33 g/mol

Solubility:    Poorly soluble in water; poorly soluble in ethanol; Soluble to 1 mg / mL in isopropanol.

Product Description


Formal Name: BisfluoroModafinil;FlModafinil;CRL-40,940

Formula   C15H13F2NO3S

Molecular Weight: 309.33 g/mol

Purity        ≥99%

CAS Number: 90280-13-0

SMILES:    C1=CC(=CC=C1C(C2=CC=C(C=C2)F)S(=O)CC(=O)N)F

Application:      CRL-40,940 (Fluoromodafinil) is an eugeroic related to and of higher potency than modafinil. Main active metabolite of Fladrafinil.

Appearance:    White to pale cream powder

Physical State: Solid

Solubility: Poorly soluble in water; poorly soluble in ethanol; Soluble to 1 mg / mL in isopropanol.

Storage:   Store at room temperature or cooler, in a sealed airtight container, protected from heat, light and humidity.

Stability:  Stable for at least two years when stored as above.

Other names

Lauflumide, Fluoromodafinil, 2-[bis(4-fluorophenyl)methylsulfinyl]acetamide, Flmodafinil, Bisfluoromodafinil, bis-(p)-fluoromodafinil, N-deshydroxyl Fladrafinil, (2-Amino-2-oxoethyl)[bis(4-fluorophenyl)methyl]sulfoniumolate

History of CRL-40,940

Adrafinil and the related family of eugeroics including Modafinil, CRL-40,941 and CRL-40,940 were originally invented in the late 1970's as part of research carried out by the French Laboratoire L. Lafon, led by Dr. Michel Jouvet.

Recommended Dosage

The research team at Lafon observed that "In man, particularly old people, it was observed that ... CRL 40940 ... administered in the form of gelules or tablets each containing 100 to 200 mg of active ingredient at the rate of 1 to 3 gelules or tablets per day, have given excellent results as arousing medicaments."

CRL-40,940 (Flmodafinil, Lauflumide) is predicted to be the main active metabolite of CRL-40,941 (Fladrafinil). Compared to Modafinil, and Adrafinil, this parent Adrafinil-like compound corresponding to Flmodafinil (CRL-40,940, Lauflumide) was observed by its inventors at Laboratoires Lafon to have similar psychotonic and eugeroic properties, but to have unique advantages: namely antiaggressive properties and improved bioavailability by the oral route, and demonstrating more potent effects than Adrafinil in animal models

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